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Type 2 Diabetes Knowledge Portal: Predicted Type 2 Diabetes Effector Genesand with
The Armstrong laboratory is focused on the mechanisms of cancer development with a focus on leukemia. One major interest in the lab is the relationship between leukemia, normal hematopoietic stem cells and the various hematopoietic cells of origin of leukemia. The lab is also studying the role of histone modifications and chromosome The Buenrostro lab seeks to advance our understanding of gene regulation biology using single-cell methods. To do this, we develop new
The Eli and Edythe L. The institute is independently governed and supported as a c 3 nonprofit research organization under the name Broad Institute Inc. Founded in , the Whitehead became a major center for genomics and the Human Genome Project. As early as , scientists at the Whitehead started pilot projects in genomic medicine, forming an unofficial collaborative network among young scientists interested in genomic approaches to cancer and human genetics. Another cornerstone was the Institute of Chemistry and Cell Biology established by Harvard Medical School in to pursue chemical genetics as an academic discipline. It facilitated small molecule screening projects for more than 80 research groups worldwide.
Broad Institute is empowering a revolution in biomedicine to accelerate the pace at which the world conquers disease. Broad Institute is a mission-driven community that brings together researchers in medicine, biology, chemistry, computation, engineering, and mathematics from across MIT, Harvard, and Harvard-affiliated hospitals, along with collaborators around the world. Broad Institute is committed to addressing medical challenges across the world, including collaborating with scientists and public health experts to address important needs in developing countries. Broad Institute fosters an environment in which scientists can take risks on bold ideas with transformative potential. Broad Institute works to build and sustain international consortia to speed discovery in areas including psychiatric research, infectious disease, cardiovascular disease, and cancer.
The Broad Institute
What's it like to build software that helps unlock insights into human disease? Software engineers talk about working at Broad in this video.
Broad Institute of MIT and Harvard was launched in to improve human health by using genomics to advance our understanding of the biology and treatment of human disease, and to help lay the groundwork for a new generation of therapies. Despite that accomplishment, scientists knew they still lacked a clear understanding of the genetic basis of disease, and how to translate that understanding into more effective prevention, diagnosis, and treatment. To reach these goals, it was clear that a new type of research institution had to be created. The traditional academic model of individual laboratories working within their specific disciplines was not designed to meet the emerging challenges of biomedicine. To gain a comprehensive view of the human genome and biological systems, they instead had to work in a highly integrated fashion. That meant working in nimble teams that combined biology, chemistry, mathematics, computation, and engineering with medical science and clinical research. It also meant working at a scale usually seen in industry, with access to world-class infrastructure.