Ferrous sulfate mechanism of action

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Ferrous sulfate

ferrous sulfate mechanism of action

Ferrous Sulfate Nursing Considerations, Side Effects, Mechanism of Action Pharmacology for Nurses

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Iron supplements , also known as iron salts and iron pills , are a number of iron formulations used to treat and prevent iron deficiency including iron deficiency anemia. Common side effects include constipation , abdominal pain, dark stools, and diarrhea. Iron pills have been used medically since at least , with an easy-to-use formulation being created in Iron supplements are used to treat iron deficiency and iron-deficiency anemia ; [9] parenteral irons can also be used to treat functional iron deficiency, where requirements for iron are greater than the body's ability to supply iron such as in inflammatory states. The main criterion is that other causes of anemia have also been investigated, such as vitamin B 12 or folate deficiency, drug induced or due to other poisons such as lead, as often the anaemia has more than one underlying cause. Iron deficiency anemia is classically a microcytic, hypochromic anemia. Generally, in the UK oral preparations are trialled before using parenteral delivery.

Ferrous sulfate is also known as Green vitriol. It is of synthetic origin and belongs to the pharmacological groups called hematological agents and iron salts. The molecular weight of ferrous sulfate is This medication is an iron supplement used to treat or prevent low blood levels of iron e. Twice the number of ferrous gluconate or ferrous fumarate tablets other forms of iron for ingestion are required to provide the amount of elemental iron in ferrous sulfate tablets For this reason, ferrous sulfate is the gold standard most commonly prescribed oral iron therapy in the UK and many other countries

Standard approaches are not appropriate when assessing pharmacokinetics of iron supplements due to the ubiquity of endogenous iron, its compartmentalized sites of action, and the complexity of the iron metabolism. The primary site of action of iron is the erythrocyte, and, in contrast to conventional drugs, no drug-receptor interaction takes place. Notably, the process of erythropoiesis, i. Accordingly, serum iron concentration and area under the curve AUC are clinically irrelevant for assessing iron utilization. Iron can be administered intravenously in the form of polynuclear iron III -hydroxide complexes with carbohydrate ligands or orally as iron II ferrous salts or iron III ferric complexes. Several approaches have been employed to study the pharmacodynamics of iron after oral administration.

Iron Supplements

Accidental overdose of products containing iron is a leading cause of fatal poisoning in children under the age of 6. Keep this product out of the reach of children. - Black Box Warnings:.



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